Diagnosing a woman's condition as "mild preeclampsia" is not helpful because it is a progressive disease, progressing at different rates in different women and appropriate care requires frequent re-evaluation for good clinical outcome.
Aims and Objective: To assess the role of Mean arterial pressure (MAP) at 11-14 weeks of gestation in prediction of preeclampsia.
Materials and Methods: Seventy eight pregnant women with 11- 14 weeks of gestation were studied at the Department of Obstetrics and Gynaecology, King George Medical University, Lucknow from September 2014 to August 2015. The women who developed preeclampsia and related complications at the end of pregnancy were grouped under GROUP 1 (n=29) and the women who did not develop any of these complications were kept under GROUP 2 (n=49). After routine antenatal examination, MAP was measured in each patient. A detailed questionnaire was filled which included demographic factors, obstetric history, past and family history, blood group and body mass index.
Results: The MAP multiple of the median (MoM) of the women who developed preeclampsia and related complications was 1.01±0.08 and that of women who did not develop complications was 0.97± 0.10 (p = 0.073).The mean MAP MoM of the women who developed early onset and late onset preeclampsia was 1.07 ± 0.05 and 1.04 ± 0.14 respectively. When compared to women who did not develop complications, the value was statistically significant for early onset preeclampsia (p = 0.029) but not for late onset preeclampsia (p = 0.299).The mean MAP MoM of the women who developed IUGR was 1.0058 ± 0.0806. The comparison of this to women who did not develop complications was not statistically significant (p = 0.2087). The area under the curve of the receiver operating curve (ROC) of MAP MoM was 0.618 (p = 0.032).
Conclusion: MAP was found to be a significant tool for predicting preeclampsia in women at 11-14 weeks of gestation.