Vol. 3, Issue 2, Part E (2017)

Material & Methods: In our study, 500 cholecystectomy specimens received over a period of 34 months in Dept. Of Pathology, Gajra Raja Medical College and Hospital. Sections were taken from Neck, Body & Fundus of Gallbladder, stained with H&E and examined under microscope.

Result: In our study of 500 cholecystectomy specimens, 494 cases were benign and only 6 cases were malignant. Chronic Cholecystitis, Acute Cholecystitis, Hyperplasia, Mucocele constitute 94%, 3.2%, 1%, .6% respectively making chronic cholecystitis (94.6%) as the commonest histopathological finding while Malignancy(Adenocarcinoma) constitute only 1.2%. Out of 500 specimens 256 patients had gall stones. Out of these 218 were female and 38 were male patients. Male to female ratio (M:F) was 1:4.5 and regarding gall stones, it was 1:5.73,showing gall stone disease predominance in females.

Conclusion: Present study emphasize on the need of a careful macroscopic as well as microscopic examination to understand the varied presentation of Gallbladder lesions and to rule out malignancy, to establish diagnosis, grading and guide management of disease accordingly.