Vol. 4, Issue 12, Part E (2018)

Abstract
To evaluate the role of cynoacrylate glue therapy and its efficacy and technical feasibility in the management of primary varicose vein due to great saphenous vein incompetency with or without incompetent perforators. This is a prospective study done in 30 patients who presented with varicose veins due to great saphenous vein reflux with or without incompetent perforators and with or without venous ulcer. All patients were subjected to cynoacrylate glue therapy in great saphenous vein followed by foam sclerotherapy for any incompetent were done at months 1, 3, 6 and 12. The study’s Primary end point was closure of the target vein at 12 month as assessed by duplex ultrasound. Technical success rate of procedure was 100%. Of all the 30 patients Saphenous vein closure rate was 96.6% at one year. There was no femoral venous extension of cyanoacrylate in any of the patients. Significant improvement was found in reduction in pain and in diameter and tortousity of saphenous vein. Ulcer healing rate was 100%.Symptoms and quality of life improved in all the patients. There was no significant adverse effects noted during the procedure and in follow up. In patients with incompetent GSV, treatment with cynoacrylate glue therapy results in high occlusion rates. Cyanoacrylate adhesive embolization and sclerotherapy is safe, easy, cost effective, minimally invasive, non surgical out- patient procedure for the treatment of primary varicose veins with 100% patient acceptance and very less morbidity compared to surgery.