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International Journal of Applied Research
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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

Impact Factor: RJIF 5.2

International Journal of Applied Research

Vol. 4, Issue 5, Part C (2018)

A clinical study of restless leg syndrome from Northern India

Choudhury SPS and Sucharita Anand
Background: Restless leg syndrome (RLS) is an under-diagnosed and infrequently treated disease. Family history of RLS symptoms is considered a criteria for categorizing the type of RLS.
Methods: This study was a prospective study and included patients presenting with symptoms of RLS and fulfilling the RLS diagnostic criteria. These patients were divided into primary and secondary type according to age of onset, asymmetry in symptoms, presence of family history and comorbidities. Clinical features were studied and compared between both the groups. Predictors for response to drug therapy were assessed in both the groups. Data was analyzed using SPSS version 23. Categorical variables were compared using chi-square test and continuous variables were compared using student t- test. p value below 0.05 was considered significant.
Results: A total of forty-five RLS patients were included. Twenty patients were of primary RLS and twenty-five patients belonged to secondary RLS group. Clinical features varied in both the groups in term of age of onset of symptoms, asymmetry in symptoms, presence of co-morbidities. Family history of symptoms was present even in fifteen patients of secondary RLS. Female patients and family history of RLS irrespective of type of RLS shows better response to dopamine agonist.
Conclusion: The presence of family history in secondary RLS patients highlights the importance of detailed family history. This may also be an indicator that perhaps all the patients of RLS are genetically predisposed and presence of co-morbidities precipitates the symptoms making them secondary RLS. Therefore, family history may not be a clinical criteria in categorizing RLS as it is positive even in patients of secondary RLS.
Pages: 189-192  |  190 Views  10 Downloads
How to cite this article:
Choudhury SPS and Sucharita Anand. A clinical study of restless leg syndrome from Northern India. International Journal of Applied Research. 2018; 4(5): 189-192.
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