Vol. 1, Issue 1, Part G (2014)

Material and Methods: A cross-sectional observational study was conducted in the Department of ENT, Mamata Medical College, Khammam, including 50 patients diagnosed with CRS. Data were collected through clinical history, physical examination, radiological evaluation (CT of paranasal sinuses), and spirometry. Asthma diagnosis was confirmed based on Global Initiative for Asthma (GINA) guidelines, focusing on reversible airflow obstruction. Statistical analysis was performed to calculate means, standard deviations, and correlations between symptoms.

Results: Of the 50 CRS patients, 36% were diagnosed with bronchial asthma. The mean severity scores for key asthma symptoms were 6.9 for intermittent wheezing, 6.5 for chest tightness, and 7.2 for reversible airflow obstruction. Radiological evaluation revealed nasal polyps in 32% of patients, with a mean severity score of 6.7, while mucosal thickening was seen in 48%, with a mean score of 7.0. The mean improvement in FEV1 post-bronchodilator was 14.3%, confirming significant reversibility of airway obstruction.

Conclusion: The study demonstrates a strong clinical correlation between CRS and bronchial asthma, with a significant proportion of CRS patients presenting with asthma. Radiological findings, such as nasal polyps and mucosal thickening, are prevalent in this group and may contribute to the severity of both conditions. Early diagnosis and integrated management of CRS and asthma could improve patient outcomes. Further studies with larger sample sizes are needed to confirm these findings and guide treatment strategies.