Vol. 1, Issue 11, Part P (2015)

Abstract
Aim: to assess concurrent chemoradiation in locally advance carcinoma cervix (figo stage iib to iva). Material and method: All patients underwent a thorough clinical examination, complete haemogram, biochemical workup, chest x-ray and ultrasound abdomen and pelvis. Staging was done as per Revised FIGO 2009. External Radiotherapy with Cobalt 60 teletherapy machine is given. Two field or four field box technique is used. Daily treatment is given from Monday to Friday. Total dose of radiotherapy given is 50 gy in 25 fractions. Manual after loading Caesium 137 BARC applicaters are used. Two ovoid and one tandem technique is used. Total dose given is 22 to 25 gy. Single session is given after external radiotherapy. The American Brachytherapy Society recommends that intracavitary applicators insertions be performed under analgesia/ anesthesia to allow examination, insertion and packing. Result: Out of total cases 38 i.e.76% had complete response, 7 i.e. 14 % had partial response and 5 i.e.10 % lost for follow up. Out of total cases, the toxicities studied i.e. the skin toxicity, vomiting and diarrhoea was 40% to 50% which was under grade 2. Conclusion: The compliance to treatment was good. The acute toxicities to combined treatment were within acceptable limits. Our observations indicate that concurrent chemo radiotherapy using cisplatinum in advanced carcinoma of the cervix, is a feasible approach towards better locoregional response.