Vol. 1, Issue 11, Part P (2015)

Abstract
Aim: Evaluating toluidine blue staining for detection of malignancy of oral cavity leukoplakia.Material and method: After recording the clinical features and photograph of clinically suspicious lesions, the lesion areas were applied prior with 1% acetic acid with cotton bud for 20 seconds and further rinsed with water. Toludine blue was applied with cotton bud for 10 to 20 seconds Then decolorized with 2% acetic acid using cotton bud for 20-30 seconds and photograph was taken Dark blue was considered as positive for lesions suspicious of malignancy, light blue retention was considered as positive for premalignant lesions unless proved otherwise by biopsy, and lesion without retension consider negative. Result: In 100 patients of leukoplakia 79(79%) were male patient and 21(21%) were female patient. Out of 100 patients no one was below 20 year age. 6% patient from 21to 30 year, 21% were from 31to 40 years of age, 20% patients from 41 to 50 years of age, 18% patients from 51 to 60 years of age, 25% of patients from 61 to70 years of age, 10% of patients were more than 70 years of age. Conclusion: As duration of leukoplakia increases its degree of dysplasia or malignant potential increases, so that early detection and diagnosis of leukoplakia is important. Staining should be routinely used as a method to assist in the choice of biopsy site and in the follow up of premalignant lesions.