Vol. 2, Issue 10, Part B (2016)

Abstract
Present investigation is focused on antibacterial activity of aqueous, petroleum ether, chloroform and acetone extract of leaves of Barleria prionitis (Family-Acanthaceae) against seven bacterial species (Lactobacillus rhamnosus, Staphylococcus aureus, Bacillus subtilis, Actinomyces viscosus, Staphylococcus epidermidis, Escherichia coli, Streptococcus mutans) which are known to cause oral diseases in human being. Similarly leaves of Barleria prionitis were evaluated for its phytochemical composition. Antibacterial activity of the extracts was determined by paper disc diffusion method using 200mg/ml concentration of extract and there % zone of diffusion was calculated. Result showed that almost all the test organism from the present study were found to be effected by all the four type of extract of Barleria prionitis leaves but pronounced inhibition of the four extract was observed for bacterial species, Lactobacillus rhamnosus. Chloroform extract was found to be more effective against the entire test microorganism.