International Journal of Applied Research
Vol. 2, Issue 10, Part I (2016)
Hepatoid adenocarcinoma of the stomach – A rare clinicopathological entity
Dr. Rajshekar Shantappa, Dr. Shubhranshu Jena and Prof. G. Suryanarayana
Hepatoid adenocarcinoma of the stomach is a rare form of gastric carcinoma with specific clinicopathological features and extremely poor prognosis.
Materials and methods: Here, we discuss 3 cases who presented in the outpatient department with pain abdomen and constitutional symptoms. Radiological examination revealed a growth involving the antrum of the stomach while the liver and spleen were normal. One case with the endoscopic biopsy suggestive of neuroendocrine tumour underwent sleeve gastrectomy and two other with biopsy suggestive of grade 3 adenocarcinoma underwent distal radical gastrectomy.
Results: In all the three cases the tumor showed hepatoid features and was immunohistochemically positive for alpha fetoprotein. All the 3 received adjuvant chemotherapy and radiotherapy. One patient showed anastomotic recurrences in one year of follow up.
Concussions: Though known to be an aggressive neoplasm early diagnosis of hepatoid adenocarcinoma can help improve the prognosis of the disease.
How to cite this article:
Dr. Rajshekar Shantappa, Dr. Shubhranshu Jena, Prof. G. Suryanarayana. Hepatoid adenocarcinoma of the stomach – A rare clinicopathological entity. Int J Appl Res 2016;2(10):567-569.