Vol. 2, Issue 11, Part A (2016)

Abstract
Acute lethal toxicity bioassay is useful for providing a measurement of the toxicity of a particular substance, and for determining the chronic toxicity so as to assess water quality criteria. The present work is aims to determine the toxicity of Cadmium Nanoparticle (20ppm) in the mud crab, Scylla olivacea with the help of histological and biochemical analysis. The overall histological results revealed that changes in the cell structure, rupture of basal lamina and complete disorganization of the gut region within 10days of exposure. The biochemical constituents total protein, carbohydrate and lipid levels drastically decreased which denotes the energy demand in organism. The antioxidant enzymes such as SOD, CAT and GPx levels were significantly increased in response to oxidative stress in the crab exposed to CdNP and the tissue damaging enzymes such as LDH, SDH, MDH were also significantly increased with increase in the days of exposure which revealed the damage of the tissue exposed to CdNP.