Vol. 2, Issue 4, Part C (2016)

Aims and Objectives: To study cases of arthropathy and to assess the severity of arthropathy in Haemophilia A patients. 

Methodology: Diagnosed cases of Haemophilia A Patients who came to Dr. D.Y. Patil Medical College, Pune were enrolled during study period i.e. October 2013 to September 2015 who fulfilled the inclusion criteria. 

A standard proforma was used to get the detailed history and the examination findings along with X ray Knee and MRI Knee were evaluated and statistically analysed. 

Results: Out of 50 subjects majority 84% were symptomatic & 16% were asymptomatic. Pain was the major complaint in 84%, followed by swelling 80% and restriction of movement in 44% cases. X ray findings in the study group, 58%- normal x ray findings, 16%- widened intercondylar notch in knee joint, 20%- minimal knee joint effusion, 2%- hyperdense expansion of the joint capsule with bony erosion & 4%- epiphyseal enlargement. MRI findings in study group, 34%- findings s/o haemophilic arthropathy, 28%- diffuse siderotic synovitis with minimal knee joint effusion, 26%- normal MRI finding, 8%- pigmented villonodular synovitis & 4%- findings s/o inflammatory arthritis. 

Conclusion: All symptomatic cases had findings suggestive of haemophilic arthropathy on MRI; even 1 asymptomatic patient had findings suggestive of haemophilic arthropathy on MRI. MRI revealed findings suggestive of arthropathy in many cases where X ray findings were normal. This showed that MRI is a more sensitive tool than X ray to detect arthropathic changes.