Vol. 2, Issue 5, Part P (2016)

Abstract
Erythema nodosum is a large, violaceous, erythematous, non-ulcerative, subcutaneous nodule with variable tenderness having every possible site of occurrence and are diagnosed clinically. It has been reported in various granulomatous as well as non-granulomatous conditions and the etiology/ etiopathogenesis still remains unclear. Our study included 24 patients with erythema Nodosum who were clinically evaluated for signs of infectious, granulomatous, cancerous and inflammatory conditions and subjected to routine work up followed by relevant investigations. Biopsy of the lesion revealed Panniculitis and Perivascular inflammatory deposits. They were followed up until completion of treatment and resolution of EN. 12 cases had tuberculosis, 6 were idiopathic, 2 had CTD, 1 had leprosy, 1 had sarcoidosis, 1 had RA and 1 with oligoarthritis. Treatment with/without NSAIDS and that of the underlying cause effectively settled EN in all cases.