Vol. 2, Issue 6, Part I (2016)

Abstract
Tetanus is vaccine preventable disease still measure cause of fatality in developing country like India. We review the history, epidemiology, pathophysiology, clinical presentation, diagnosis and management of tetanus along with series of 3 cases reported in our district hospital in last 2 years. Among 3 cases, two were of otogenic tetanus in children with incomplete or unknown immunization status and 1 case was reported in adult who had not received tetanus vaccine for his wound after road traffic accident. The differential diagnosis of tetanus may be confusing and survival depends on the early diagnosis and treatment with antitoxin, as well as adequate supportive care. All patients had received supportive care immediately. After conformation of diagnosis clinically and/or microbiologically, tetanus toxoid and immunoglobulin were given to patients due to limited resources. Adult patient died due to respiratory failure while both child were recovered with treatment. To conclude, as tetanus is vaccine preventable disease it is important to strengthen existing immunization program against tetanus and educating people and health care worker regarding importance of immunization against tetanus.