International Journal of Applied Research
Vol. 2, Issue 8, Part F (2016)
Antibacterial activity of different solvent extracts of Solanum xanthocarpum Sch & Wend (root) against pathogens isolated from diabetic foot ulcer
In the current study, aqueous and solvent extracts of S. xanthocarpum root against some clinical bacterial isolates viz., Proteus, E. coli, Klebsiella, Pseudomonas, Enterobacter and Staphylococcus aureus recorded varied interesting results. Aqueous extract, solvent extracts were tested by well diffusion, disc diffusion and MIC methods. DMSO and Kanamysin served as negative and positive control respectively. In well diffusion, aqueous extracts was found ineffective against the pathogenic bacteria, rather than Kanamycin exhibited the zone of inhibition against E. coli, Klebsiella and S. aureus. Disc diffusion recorded the inhibitory property of the chloroform and Ethanolic extracts on all organisms tested, however, Pseudomonas and S. aureus exhibited wide susceptibility. MIC showed concentration dependent gradient decreasing in the level of inhibition against all the organisms. Ethanol and ethyl acetate extract were proved to be most effective though Pseudomonas and S. aureus were found resistant against the highest concentration.
How to cite this article:
Shubha KS, Lakshmidevi N. Antibacterial activity of different solvent extracts of Solanum xanthocarpum Sch & Wend (root) against pathogens isolated from diabetic foot ulcer. Int J Appl Res 2016;2(8):388-393.