AbstractBackground: Thrombocytopenia can happen when the spleen gets sucked up, when platelets are destroyed more quickly, or when the bone marrow doesn't grow enough. A bone marrow test is the only way to be sure of what is causing thrombocytopenia, but it is expensive and invasive.
Materials and Methods: A prospective observational and case control study was carried out at Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, India. The researchers were part of the Department of Pathology's haematology branch. This study looked at the association between age and thrombocytopenia, as well as the therapeutic relevance of platelet volume characteristics measured by an automated blood cell counter.
Results: This study assessed the utility of platelet parameters from bone marrow examinations, compared to automated blood cell counter results, in differentiating between hyperdestructive and hypoproductive thrombocytopenia etiology. The patients were adults, aged between 11 and 70 years. Thirty percent of patients are found within the age range of 41 to 50, with eighteen cases documented.
Conclusion: The platelet indices in the hyper-destructive group in this study are elevated, which may aid in differentiating between hyper-destructive and hypo-productive causes of thrombocytopenia.