AbstractBackground: Tuberculosis-associated obstructive pulmonary disease (TOPD) is an under-recognized consequence of treated pulmonary tuberculosis (TB), leading to chronic respiratory complications. This study aimed to evaluate the prevalence and clinico-radiological profile of TOPD in non-smoking adults.
Materials and Methods: This cross-sectional study was conducted over one year in two tertiary care hospitals, enrolling 100 non-smoking adults previously treated for pulmonary TB. Clinical data, spirometry results, and radiological findings were collected and analyzed using SPSS software. Severity of airflow obstruction was graded, and correlations with radiological and clinical findings were assessed.
Results: Among 100 patients, 50% exhibited obstructive spirometry patterns, with moderate obstruction being the most common severity (48%). Radiological abnormalities included parenchymal fibrosis (97%), bronchiectasis (59%), and thin-walled cavities (35%). Dyspnea (70%) and cough (57%) were the most frequent symptoms. Significant correlations were noted between spirometry severity, radiological findings, and lung lobe involvement.
Conclusion: This study underscores the significant burden of TOPD among non-smoking adults. Comprehensive follow-up care, including spirometry and radiological assessments, is essential for the timely detection and management of airflow obstruction in post-TB patients.