Vol. 4, Issue 4, Part D (2018)

Objective: This investigation is aimed to determine the prevalence and correlation of phenotypic virulence traits and antibiotic resistance among the UPEC isolated.

Materials and Methods: A total 426 urine samples from clinically suspected UTI patients were processed by standard microbiological procedures. The virulence factors of 152 E. coli, Haemolysis, Mannose sensitive/resistant haemagglutination, serum resistance, cell surface hydrophobicity, Gelatinase were studied. The antimicrobial susceptibility was done as per Clinical and Laboratory Standard Institute Guidelines. 50 stool sample were included in study as control.

Result: Hemolysin production was seen in 30.92%, hemagglutination in 51.97%, Cell surface hydrophobicity in 38.15%, serum resistance in 52.63%, gelatinase in 40.13% and siderophore production in 63.81% isolates. Nitrofurantoin was found to be most Effective followed by, imipenum and Amikacin.

Conclusion: The knowledge of virulence factors of E. coli and their AST will help in better understanding of organism and in treatment of UTI.