Vol. 4, Issue 6, Part B (2018)
Clinico-haematological parameters in dengue in adults: a retrospective study from a tertiary care hospital
Background: Dengue is an arboviral infection, endemic in India. The clinical presentation can vary for fever with rashes to severe bleeding tendencies as in dengue hemorrhagic fever (DHF), and dengue shock syndrome, leading to death. Various laboratory parameters get deranged in Dengue, like total platelet counts, haematocrit and total leucocyte counts. Monitoring these symptoms and lab parameters can help to prevent the cases from complications. Aims and Objectives: This study was undertaken to study clinical presentations, the haematological and biochemical parameters and the outcome of the patients suffering from dengue. Materials and methods: This was a retrospective study conducted in the department of Microbiology, Father Muller Medical College Hospital, Mangalore. All patients above the age of 18 years who were diagnosed as dengue, with positive result for NS1Ag or IgM or IgG antibodies were included in the study. The data from individual patients were noted down from individual files and entered in to the Microsoft excel. Data collected will be analysed by frequency and percentage Results: The study included 130 patients, two third of which were males. Majority of the patients were of the age group of 18-30 years 48(36.92%) and only 12 patients’ (9.23%) were with serious presentation so that be to managed in Intensive care unit. Most of the patients presented with typical symptoms of Dengue i.e., fever 128 (98.46%), 104 (80%) patients had thrombocytopenia. The ultrasonography of abdomen (USG) showed splenomegaly in 24.62% of the patients. The pleural effusion was seen in 10 patients, and ascites seen in 15 patients. Two patients succumbed to death, with best of the efforts. Conclusion: In Dengue infection, some of the signs and symptoms of low platelet counts and plasma leakage, like bleeding gums, malena, haematuria, and pedal edema, ascites, pleural effusion, respectively, needs to monitored carefully so that the required supportive therapy to be initiated at the earliest so as to reduce the mortality.
How to cite this article:
Thomas George, Ramakrishna Pai Jakribettu, Sharanya Yesudas, Andrew Thaliath, Michael LJ Pais, Soniya Abraham, Manjeshwar Shrinath Baliga. Clinico-haematological parameters in dengue in adults: a retrospective study from a tertiary care hospital. Int J Appl Res 2018;4(6):88-91.