AbstractBackground: Proliferative diabetic retinopathy (PDR) remains a leading cause of blindness worldwide. Pars plana vitrectomy (PPV) is a standard surgical procedure for managing advanced PDR complications, such as vitreous hemorrhage, tractional retinal detachment (TRD), and diabetic macular edema (DME). This study aims to assess the outcomes of PPV in patients with PDR, focusing on visual and anatomical recovery post-surgery.
Materials and Methods: This prospective interventional study was conducted at the Department of Ophthalmology & General Medicine Kamineni Institute of Medical Sciences, between June 2017 and May 2018. Seventy-five patients with PDR undergoing PPV were included, with exclusion criteria involving other retinal vascular disorders or systemic contraindications. Baseline assessments included best-corrected visual acuity (BCVA), OCT, and fundus fluorescein angiography. Surgical procedures were performed under local anesthesia, with postoperative management including antibiotic and steroid eye drops. Patients were followed up at 1, 3, and 6 months.
Results: The most common indication for vitrectomy was vitreous hemorrhage (52%), followed by TRD (14.67%) and combined TRD and VH (17.33%). Postoperative visual acuity showed significant improvement in all groups, with the vitreous hemorrhage group achieving a BCVA of 0.19 (~6/36) at 3 months. The TRD group exhibited slower initial recovery but still showed statistically significant improvement in VA at 3 months.
Conclusion: PPV demonstrates significant potential in improving visual acuity and retinal outcomes in patients with diabetic retinopathy. While the vitreous hemorrhage group showed the most pronounced visual recovery, TRD cases require more individualized management due to slower postoperative recovery. These results underscore the importance of timely surgical intervention and tailored approaches for different PDR subtypes.