Vol. 4, Issue 7, Part D (2018)

Abstract
Background: Prior detection of cardiac cases allow cost-effective & better triage and well-timed management of these patients. Study was conducted to evaluate the prognostic significance of plasma adiponectin, troponin I in a group of patients with ST segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction. These parameters were also compared with other predictors like Troponin I and CK-MB. Methods: This study was based on the 72 patients with AMI of whom 42 had a diagnosis of STEMI, and 32 had NSTEMI. Duration of study was June to December 2017. Patients having chest pain that was indicative of myocardial infarction within first 12 hours after the onset of symptoms were included in the study. Adiponectin, troponin I were estimated using ELISA method. Level of CK-MB was measured by Auto-analyser using standard kit of Siemens. Results: Mean age of patients with STEMI in males was (62.5yrs) and in females (58.5 yrs) and with NSTEMI age in males was (61.5yrs) and in females (57 yrs). Higher proportion NSTEMI/UA cases in comparison to STEMI cases had hypertension, diabetes mellitus and had been females. 3.05% of NSTEMI/UA cases died during hospital treatment and females had higher mortality risk (4.5%). It was observed that the level of adiponectin and CKMB was elevated in patients with STEMI than patients with NSTEMI and significant difference was observed (p<0.05). Level of TnI was increased in patients with NSTEMI as compared to patients with STEMI but significant difference was not seen. Conclusion: The rate of ACS (especially that of STEMI) remains high. Male patients with ACS have higher incidence of STEMI than NSTEMI/UA. However, the markers of STEMI are increased level of adiponectin and the markers of NSTEMI are troponin I and CKMB.