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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF
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Vol. 4, Issue 9, Part A (2018)
Atypical haemolytic uremic syndrome in patient of CKD
Atypical haemolytic uremic syndrome in patient of CKD
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Abstract
Atypical HUS is characterised by microangiopathic haemolytic anaemia, thrombocytopenia, and renal insufficiency. Factor H deficiency is one of the main cause of atypical HUS, wherein anti-complement factor H antibody is high leading to deficiency of factor H.
Atypical HUS is characterised by microangiopathic haemolytic anaemia, thrombocytopenia, and renal insufficiency. Factor H deficiency is one of the main cause of atypical HUS, wherein anti-complement factor H antibody is high leading to deficiency of factor H.
We report a case of atypical HUS due to factor H deficiency in a patient of CKD which presented with fever, vomiting (without loose stools) and generalised Edema. OlE child looked pale, pitting type of Edema present, B.P was raised. Investigations showed evidence of microangiopathic haemolytic anaemia, thrombocytopenia, renal insufficiency. Anti-compliment factor H assay was raised. USG confirmed features of CKD. Dialysis was started, FFP was infused with little improvement. Patient responded well to plasmapheresis. Patient improved clinically.
Pages: 25-27 | 735 Views 58 Downloads
How to cite this article:
Dr. Vineeta Pande, Dr. Nadeem Azad, Dr. Manoj Matnani, Dr. Mayank Surana, Dr. Samira Narayan. Atypical haemolytic uremic syndrome in patient of CKD. Int J Appl Res 2018;4(9):25-27.
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Research Journals