AbstractBackground: Indian sub-continent harbours a global threat in the form of epicenter of multidrug resistant
Plasmodium falciparum. Kidney involvement is relatively frequent in infections by
P. falciparum and
P. malariae, but has also been described in the infection by
P. vivax.
Aims and Objectives: To find out the prevalence of AKI in malaria patients.
Materials and Methods: Hundred malaria positive patients were studied in the department of medicine, Hamidia hospital and Gandhi Medical College Bhopal from March 2015 to August 2016. Detailed history regarding other systemic diseases and routine investigations including PS for mp, was performed. Malaria was differentiated on the basis of the different parasite present in the blood. Serum creatinine was measured and eGFR was estimated. AKI was defined using the KDIGO criteria.
Results: Incidence of AKI among the patients with falciparum malaria was 5 (10.86%). Incidence of AKI among the severe cases of falciparum malaria (n=22) was 40.90% (n=9). Incidence of AKI among the patients with P vivax malaria was 7.69% (n=3).
Conclusion: Incidence of AKI in patients with severe form of falciparum malaria is high. Even, P vivax infection can also lead to the development of AKI in some cases. Serum creatinine measurement is recommended to diagnose AKI in malaria patients.