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International Journal of Applied Research
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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

IMPACT FACTOR (RJIF): 8.4

Vol. 5, Issue 2, Part C (2019)

A novel synthesis, characterization and antibacterial studies of quinaxoline derivative

A novel synthesis, characterization and antibacterial studies of quinaxoline derivative

Author(s)
Rajeev Kumar Karna
Abstract
A novel synthesis, Characterization and their antibacterial studies of benzoderivative of quinoxaline has been reported. 3-nitro anilines are reacted with chloroacetyl chloride in presence of acetone to give 2-chloro-N-(3-nitrophenyl)acetamide which when reacted with 2-amino-4-(4-chlorophenyl)-1,4-dihydrocinnolin-3(2H)-one in presence of dry pyridine to give the final target. The structures of synthesized compounds are confirmed by their IR and 1H-NMR spectral data. Melting point of the compound has been determined by open capillary tube and hence uncorrected. TLC of the compound has been carried out by using n-hex:EA (1:1) solvent.
Pages: 268-269  |  443 Views  51 Downloads
How to cite this article:
Rajeev Kumar Karna. A novel synthesis, characterization and antibacterial studies of quinaxoline derivative. Int J Appl Res 2019;5(2):268-269.
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