Vol. 5, Issue 5, Part B (2019)

Abstract
Background: The gram-negative bacteria; P aeruginosa is often a motive of nosocomial infections like; meningitis, bacteremia, pneumonia, and urinary tract infections. P aeruginosa is known as an emerging motive of nosocomial infections worldwide. Colistin is the ultimate line treatment for multidrug-resistant A. Baumannii, and unfortunately, its resistance to colistin is being suggested from all around the world. Materials and Method: This prospective observe became carried out at some point of Jeb 2016 to Jan 2018 (2 years) on one hundred P aeruginosa samples remoted from Wound swabs, urine, respiratory secretions, and blood of sufferers admitted to the intensive care unit of IMS and SUM Hospital, Bhubaneswarm India. The micro-organism were identified through microscopy and biochemical tests. The disk diffusion method with colistin disk (Himedia, Mumbai, India) became utilized to discover the resistance to colistin. Results: A total of a hundred P aeruginosa microorganism have been identified, of which 93 had been sensitive and seven were proof against colistin, respectively, consistent with the disk diffusion test. Conclusion: The outcomes confirmed that the resistance of P aeruginosa to colistin, as the final line remedy, is rising in Bhubaneswar, Odisha, India.