Vol. 5, Issue 6, Part D (2019)

Abstract
The purpose of the study was to evaluate the total phenolic content, anti-oxidant activities, and anti-proliferative activity of buckwheat and wheat using different solvents. Both the samples of each extract were evaluated for DPPH radical scavenging activity, reducing power, lipid per-oxidation, H₂O₂ scavenging activity, hydroxyl radical scavenging activity. The results showed that both the samples with all the solvents exhibited appreciable amounts of total phenolic compounds and anti-oxidant activity but methanol proved to be best extract in all the tests except for DPPH radical scavenging activity which was found to be higher in ethanol. Buckwheat was found to be a more potent anti-oxidant and anti-proliferative source with higher total phenolic content (70.62 GAEµ/ml) when compared to wheat (60.4mg GAEµ/ml). The anti-proliferative activity of buckwheat and wheat was tested in C-6 cells. Both, buckwheat and wheat inhibited the growth of cancer cells but buckwheat (49.58%) proved to be more potent anti-proliferative source when compared to wheat (35.59%).