Vol. 8, Issue 2, Part D (2022)

Abstract
Purpose: To examine central macular and peripapillary retinal nerve fibre layer (RNFL)/ganglion cell layer (GCL) thickness in uniocular amblyopic patients.Methods: This cross sectional observational prospective study conducted on 20 patients (8-18 years) diagnosed with uniocular amblyopia. Central Macular Thickness (CMT) and NFL/GCL thickness was measured by OCT (NIDAC RS 3000 ADVANCE) and data was compared with normal fellow eye.Results: In a study group of 20 children (males=14, females= 6), the mean values of CMT observed in amblyopic eyes is (354 mm) and those of healthy fellow eyes is (253.55 mm). Also, RNFL/GCL thickness was determined in these children where mean value in amblyopic eyes is (121.89 mm) and those of healthy fellow eyes is (119 mm). Amblyopic eyes had slightly greater central macular thickness (macular map) as compared to the healthy fellow eye (p-value of (<0.05). The values of RNFL/GCL thickness showed no change (p- value (>0.05). Conclusions: In children aged predominantly 8 and 18 years, central macular thickness may be increased in eyes with amblyopia, although it is uncertain if this precedes or follows the development of amblyopia. No differences in peripapillary RNFL thickness were found when compared with normal eyes.