Vol. 8, Issue 2, Part G (2022)

Introduction: Urothelial carcinoma is a very common malignancy worldwide. Urine cytology helps to detect high-grade urothelial carcinoma (HGUC). The Paris System (TPS) Working Group, has proposed and published a standardized reporting system that includes specific diagnostic categories and cytomorphologic criteria for the reliable diagnosis of HGUC. The aim of this study is to analyze the urine cytology smears by The Paris System and to assess the frequency of various categories.

Methods and Methodology: This is a cross sectional study done in a tertiary care hospital. 100 urine samples were received in our department. The data collected were tabulated and categorized according to TPS system: negative for high-grade urothelial carcinoma (NHGUC), atypical urothelial cells (AUC), low-grade urothelial neoplasm (LGUN), suspicious for high-grade urothelial carcinoma (SHGUC), and high-grade urothelial carcinoma (HGUC).

Results: The male: female ratio was 5.2: 1. The percentage of various categories as per the TPS are: NHGUC 48%, AUC 23%, LGUN 1%, Suspicious for HGUC 13% and HGUC 15% respectively. The incidence of HGUC was highest in the age group of 71-80 years.

Conclusion: Urine cytology is a valuable, non-invasive and easy procedure suitable for all patients with urinary symptoms for the detection of infectious conditions, pre-malignant conditions and malignancy specifically HGUC.