Vol. 8, Issue 4, Part F (2022)

Abstract
Achyranthes aspera is the herb and one of the medicinal plant in India, belongs to the family Amaranthaceae which is used to treat various infections. Achyranthes aspera is called as Nayurivi in Tamil. The plant parts (leaf, stem and root) of Achyranthes aspera were collected and extracted with solvents such as ethanol, methanol and acetone. Antibacterial study was carried out by well diffusion method using ATCC pathogens, Staphylococcus aureus (ATCC25923), Pseudomonas aeruginosa (ATCC 27853) and Escherichia coli (ATCC 25922). Acetone extract of the leaf showed maximum inhibition of 25mm against P. aeruginosa. Stem extracts showed maximum inhibition of 16mm against Staphylococcus aureus, Pseudomonas aeruginosa and E. coli. Ethanol root extracts of Achyranthes aspera showed the maximum inhibition of 17mm against Pseudomonas aeruginosa Among the 3 plant parts of Achyranthes aspera, acetone extracts of the leaf showed maximum inhibition of 25mm against Pseudomonas aeruginosa. The mass chromatogram of Achyranthes aspera leaf extract showed 48 different phytochemical compounds. Free radical scavenging activity exhibited by leaf extract of Achyranthes aspera using DPPH assay was 50%, where the positive control, ascorbic acid showed 87%.