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International Journal of Applied Research
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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

g-index: 90

Vol. 11, Issue 1, Part E (2025)

Clinical evaluation of traditional Unani herbal extracts comprising Lupinus albus, crocus sativus, and Cucumis melo seeds for acne vulgaris: A single-arm clinical trial

Clinical evaluation of traditional Unani herbal extracts comprising Lupinus albus, crocus sativus, and Cucumis melo seeds for acne vulgaris: A single-arm clinical trial

Author(s)
Hajra Parveen, Imrana Hafeez and Zoheb Alam Khan
Abstract
Background: Acne vulgaris, or Busoore labaniya, is a common dermatological disorder affecting up to 80% of adolescents. While not life-threatening, it significantly impacts self-confidence and mental health, necessitating effective treatment. This study aimed to evaluate the efficacy of a Herbal formulation containing Turmus, Magz-e-Tukhme Khashkhash Safed, Magz-e-Tukhme Kharpaza, Magz-e-Tukhme Baqla, Magz-e-Badam Talkh, and Zafran in managing acne vulgaris.
Methods: A single-arm clinical trial was conducted at the outpatient departments of Aligarh Unani Medical College and ACN Hospital, Aligarh, Uttar Pradesh. A total of 100 patients (aged 12–30 years, both sexes) with clinically diagnosed acne vulgaris were enrolled after providing informed consent. The Unani formulation was administered locally twice daily for 15–20 minutes over 45 days. Acne severity and treatment efficacy were assessed using Cook’s Acne Grading Scale at baseline, day 15, day 30, and day 45. Subjective parameters, including pain, tenderness, dryness, and pigmentation, were also evaluated.
Results: Significant improvements were observed in acne severity and associated symptoms. Cook’s Acne Grading Scale scores showed a marked reduction (p < 0.0001), with substantial improvement in lesion size (p < 0.00001). Subjective outcomes, including reduced pain, tenderness, dryness, and pigmentation, were evident by day 15 and progressively improved over the treatment period.
Conclusion: The Unani formulation demonstrated significant efficacy in managing acne vulgaris, improving both clinical and subjective outcomes. These findings suggest its potential as a safe and effective alternative treatment for acne vulgaris.
Pages: 345-349  |  92 Views  34 Downloads


International Journal of Applied Research
How to cite this article:
Hajra Parveen, Imrana Hafeez, Zoheb Alam Khan. Clinical evaluation of traditional Unani herbal extracts comprising Lupinus albus, crocus sativus, and Cucumis melo seeds for acne vulgaris: A single-arm clinical trial. Int J Appl Res 2025;11(1):345-349. DOI: 10.22271/allresearch.2025.v11.i1e.12307
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