Vol. 11, Issue 4, Part A (2025)

Hypocalcemia is an set up cause of neurological and psychiatric ailment with numerous clinical appearances. The point of this ponder was to decide the result of extreme neuropsychiatric indications of persistent hypocalcemia after adjustment of calcium levels. Clinical and research facility information of 15 patients seen between September 2024 and February 2025 were reflectively analyzed. Serum calcium values were measured in all cases. Most patients (n = 9; 60%) had generalized tonic-clonic shakings whereas three had seizures with maniacal highlights. Development disarranges were watched in 4 patients and one had candida meningitis. Eight of the 15 patients had essential hypoparathyroidism and one had mucocutaneous candidiasis. One had pseudohypoparathyroidism and two had vitamin D lack. All patients moved forward with calcitriol and calcium treatment. Five of the 15 patients with writhings were taking anticonvulsants. Dystonia was watched in two patients. In three patients who had these indications some time recently taking the sedate, mental indications made strides, but they did not vanish. Grown-up patients who have seizures or neuropsychiatric side effects ought to have their serum calcium levels checked frequently. The conclusion of seizure clutters caused by unremitting hypocalcemia is best made when serum calcium levels move forward. Development disarranges moved forward altogether. There was no critical advancement in mental side effects when serum calcium levels progressed. Moo calcium levels, or hypocalcemia, can cause mental wellbeing issues, as calcium makes a difference direct disposition and cognitive work.

•Mood disorders-Low calcium levels have been linked to anxiety, depression, stress, anger, and mood imbalances.

•Neurotransmitter function- Calcium ions help release neurotransmitters like serotonin and dopamine, which are important for mood regulation. Low calcium levels can affect neurotransmitter function.

•Cognitive function-Low calcium levels can disturb neuronal and cognitive function.

•Irritability-Calcium is a natural sedative that helps control mood. When calcium levels are low, people may feel more pressured or irritated.

Causes of low calcium

•Low dairy intake

•Parathyroid disease, which can cause calcium imbalances

Other factors that may affect mental health

•Poor oral health, such as tooth erosion, cavities, gingivitis, and periodontitis.

•Anemia, which can be caused by chronic kidney disease.

Patients with hypocalcaemia as a consequence of hypoparathyroidism can have varied neuropsychiatric presentations such as intractable seizures, depressive symptoms, psychosis, generalized parasthesias and extrapyramidal syndrome.