Vol. 11, Issue 7, Part C (2025)

Abstract
Drug induced liver injury is a well known cause of transaminitis, in this case, labetalolol, as an etiological factor of liver injury complexly intertwined with a clinical picture of biliary pancreatitis. This clinical case report holds significance in patients with gestational or chronic hypertension where a marked rise in liver enzymes obviates further workup in the direction of partial HELLP syndrome or differentials such as acute fatty liver of pregnancy, nonalcoholic steatohepatitis, cholelithiasis, infectious diseases or autoimmune diseases, therefore further necessitating delivery.Interestingly, in this case report, multiple exhaustive investigations after followup with a multidisciplinary team of experts were all rendered negative only to point to labetalol being the singular cause of hepatotoxicity and biliary pancreatitis, thereof potentially averting unnecessary iatrogenic preterm delivery measures. On delving deeper into the specifics of this case report after meticulous workup for other causes of liver injury and unsettling liver and pancreatic enzymes, a simple resort to stop labetalol and switch to alternate antihypertensive proved to be useful in improving the clinical picture liver injury.