Vol. 11, Issue 9, Part B (2025)

Abstract
Severe burn injuries in children remain a major challenge in clinical practice, with allografts increasingly used as temporary biological dressings to promote wound healing, reduce infection, and minimize repeated autografting. The present study systematically reviewed 23 research articles published between 2000 and 2023 to evaluate the effectiveness of allograft interventions in pediatric burn care. Following PRISMA guidelines, relevant studies were selected through predefined inclusion and exclusion criteria, covering randomized controlled trials and observational studies. Together, the studies included more than 2,500 pediatric patients with varying burn total body surface area (TBSA). Findings revealed that both cryopreserved and fresh allografts improved wound closure rates, enhanced graft survival, and reduced hospital stay, with randomized trials particularly highlighting better graft take and reduced morbidity. Observational evidence further supported improved survival and functional recovery, especially in children with burns exceeding 30% TBSA. Overall, the synthesis confirms that allografts are a valuable adjunct in pediatric burn management, though challenges related to accessibility, cost, and standardization remain. Future research should focus on developing uniform protocols, assessing long-term functional outcomes, and exploring cost-effectiveness in diverse healthcare contexts.