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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

Impact Factor: RJIF 5.2

International Journal of Applied Research

Vol. 3, Special Issue 3, Part J (2017)

An efficient synthesis of azlactone derivatives catalyzed by cellulose sulphuric acid

Author(s)
KF Shelke, RE Khadse, NS Thakare
Abstract

A simple and efficient route has been developed for the synthesis of 4-Arylidene-2-phenyl-5(4)-oxazolones (Azlactone) derivatives through the condensation of aromatic aldehydes and hippuric acid in acetic unhydride medium in presence of catalytic amount of cellulose sulphuric acid (CSA) at 60 °C is described. The reaction goes smoothly, simple experimental procedure, easy work- up and good to excellent yield of the products are the advantages of the present work. Moreover, the CSA was successfully reused for three cycles without significant loss of activity.
Pages: 313-315  |  671 Views  12 Downloads
How to cite this article:
KF Shelke, RE Khadse, NS Thakare. An efficient synthesis of azlactone derivatives catalyzed by cellulose sulphuric acid. International Journal of Applied Research. 2017; 3(3S): 313-315.
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