Vol. 4, Issue 8, Part C (2018)

Abstract
Introduction: Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia, myalgia, rash, nausea, and vomiting. Infections are caused by any of four virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4).The incidence of dengue is increasing in most tropical areas throughout the world. Dengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the co-circulation of multiple serotypes),and the emergence of dengue hemorrhagic fever in new geographic regions. In 1998 this mosquito-borne disease is the most important tropical infectious disease after malaria, with an estimated100 million cases of dengue fever, 500,000cases of dengue hemorrhagic fever, and 25,000deaths annually.