Vol. 1, Issue 10, Part K (2015)

Abstract
Context: Emerging resistance to Vancomycin is a matter of serious concern as it is the drug of choice for the management of infections with multidrug resistant gram positive bacterial strains. Substantial proportions of bacterial strains are developing resistance to Vancomycin. Aim: To study the pattern and extent of Vancomycin resistance among different bacterial isolates obtained from blood specimens. Method and Material: A cross sectional observational study was conducted in a tertiary care teaching hospital of central India. The data of Vancomycin resistance was obtained from culture and sensitivity reports from Department of Microbiology. Statistical analysis used: Ninety five percent Confidence interval of proportion of Vancomycin resistant isolates was calculated. Result: Blood culture positivity rate was found to be 39.4%. The isolates having growth of gram positive bacteria were found to be 16.6% of all the positive growth. The most common gram positive bacteria were staphylococcus. The resistance to Vancomycin was found to be 24.5% among gram positive bacteria. Conclusion: The information and data regarding pattern of Vancomycin resistance may be helpful to solve the problem of emerging Vancomycin resistance. The reduction in the indiscriminate use of Vancomycin is an important approach to impede its resistance.