Vol. 1, Issue 12, Part O (2015)

Abstract
Biomarkers are biological constituents that can helps in detecting of pathological conditions and normal physiological process in the body in approximately precise manner In preclinical studies such as cellular or animal modules particular biomarkers can be monitored. Biomarkers can be used in drug development through replacing endpoints to substitute for clinical points that permits for early evaluation of the drug advantage/effectiveness This work includes hypothesis and interpretation of using biomarkers in detection pathological conditions in three main biological abnormalities, first; Biomarkers used for detection of abnormalities result from autoimmune diseases second; Biomarkers used to detect abnormalities in blood caused by infectious agents third; Biomarkers used to detect abnormalities in CNS caused by infectious agents.