Vol. 1, Issue 4, Part G (2015)

Introduction: Tobacco smoking is recognised as a distinct risk factor for both oropharyngeal and laryngeal malignancies. It is of the utmost importance to educate the general people about the harmful repercussions that tobacco use has on malignancies. The purpose of this study is to investigate the connection between smoking and the development of laryngopharyngeal cancer at Sangareddy Teaching Hospital.

Materials and Methods: All of the 820 patients who participated in this research gave their informed permission before the trial was carried out. The patients were asked to provide their entire health history, as well as their clinical and laboratory data, which were then gathered from discharge summaries or the medical record department. For the purpose of conducting a laboratory examination of nicotine levels, blood samples were taken.

Results: The majority of the patients were between the ages of 21 and 40 (65.24 percent), with males making up the majority (91.7 percent). Cancer was found in the pyriform sinus in 75% of the patients, followed by cancer in the posterior pharyngeal wall in 9% of the cases. Nearly ninety percent of the cases were squamous cell carcinoma. The number of samples in which positive nicotine levels were found was much lower than the total.

Conclusion: A significant contributor to the development of laryngopharyngeal malignancies seems to be the use of tobacco products and tobacco products for an extended period of time and in excessive amounts. Putting an end to tobacco use leads to a significant reduction in the number of pathologic lesions that are present in the laryngopharynx.