International Journal of Applied Research
Vol. 1, Issue 8, Part E (2015)
A Study of Cord Blood Lipid Profile in Preterm and Term Neonates
Sreekarthik KP, Shubha Jayaram, Aravind Karinagannanavar, Sumana Sindhuram V
Background: According to foetal origin hypothesis, atherosclerosis originates during foetal period. Studies have shown an enhanced rate of coronary heart disease among men and women whose birth weights were at a lower end of normal range. Objectives: 1) to compare lipid profile of umbilical cord blood of preterm and term neonates. 2) To compare lipid profile between male and female preterm neonates. 3) To determine Atherogenic Index of Plasma (AIP) and compare the obtained values between preterm and term neonates. Methodology: A case-control study was conducted in OBG Department, Cheluvamba Hospital, from June 2014 to July 2014. All the preterm deliveries reported during this period were included in the study. Gender matched term babies were selected as controls. The proforma included socio-demographic profile, obstetric history and cord blood lipid profile among preterm and term neonates. rnResults: The mean gestational age in term and preterm neonates was 39.16 ± 1.01 weeks and 33.13 ± 3.28 weeks and birth weight was 3.13 ± 0.45 kg and 2.04 ± 0.55 kg respectively. Among term and preterm neonates the mean value of serum cholesterol, serum LDL and and Atherogenic Index were more among preterm neonates except serum Triglycerides, serum HDL, serum VLDL and the difference was not statistically significant. Among male and female preterm neonates the mean value of serum cholesterol, serum triglyceride, serum HDL, serum LDL and serum VLDL were more among female preterm neonates except Atherogenic Index and the difference was not statistically significant except HDL. Conclusion: Altered cord blood lipid profile values were found in preterm neonates in comparison with term neonates except HDL. Atherogenic Index of Plasma was more in preterm neonates in comparison with term neonates.
How to cite this article:
Sreekarthik KP, Shubha Jayaram, Aravind Karinagannanavar, Sumana Sindhuram V. A Study of Cord Blood Lipid Profile in Preterm and Term Neonates. Int J Appl Res 2015;1(8):276-281.