Vol. 1, Issue 8, Part M (2015)

Background: Neonatal hyperbilirubinemia is associated with substantial morbidity and mortality, and ABO incompatibility is a leading cause of this condition. Thus, it is crucial to do newborn screenings for those at risk.

Materials and Methods: A descriptive study was done over the period spanning from May 2014 to April 2015. The participants in this study were selected randomly from the population of children born to O-positive women who underwent caesarian section at the Department of ENT, Mayo Institute of Medical Sciences, Barabanki, Uttar Pradesh, India.

Results: The study involved a total of 120 newborns who were identified as being at a high risk for ABO incompatibility. A cohort of 100 neonates exhibited clinical jaundice, with approximately 13% of these instances advancing to a more severe manifestation of jaundice. Our study exclusively included newborns with weights ranging from 2.5 to 4 kg.

Conclusion: There was no indication of notable reticulocytosis in cord blood from infants at risk of ABO incompatibility. Babies with a positive direct coomb's test developed pathological hyperbilirubinemia in 100% of cases, although only 15% of children with pathological hyperbilirubinemia had this result.