Vol. 2, Issue 1, Part F (2016)

Abstract
The human microflora comprises a complex ecological system maintaining an executive homeostasis that plays important role in human health, such as, by stimulating the immune response, aiding digestion of food materials and helping to prevent pathogens from colonizing on epithelial surfaces. Folic acid, also called folate or folacin, is a vital raw material for production of Red Blood Cells (RBC), as well as norepinephrine and serotonin (important components of nervous systems). In human, non-pathogenic strains ofintestinal flora bacteria- Escherichia Coli (E. Coli), impart vital role in favour of synthesizing folate from simpler compounds and focuses a significant insight paying regards to conservation of biodiversity especially in case of pregnant women. We have analyzed the consequences and the capability of synthesizing folate by E. Coli, present in human intestine as a beneficial microbial flora, by utilizing different software, widely used in Bioinformatics andour review suggest that, conservation of different features of E. Coli appears to be very important in case of pregnant women to prevent the offspring from several vulnerable stages.