International Journal of Applied Research
Vol. 2, Issue 6, Part B (2016)
Antibacterial activity of Acacia nilotica fruits extract against pathogenic bacteria
Sara M Gmaraldeen, Amira A Magzoub, Ali M Badri, Mohamed I Garbi and Mahmmoud S Saleh
Microbial infections are major public health problems in the developing countries. Infectious disease consider as the most cause of death for approximately one-half of all deaths in tropical countries. This study was carried out to investigate the in-vitro antibacterial activity of Acacia nilotica methanolic fruits extract against clinical isolates performed by cup-plate agar diffusion method against 5 Gram negative bacteria Escherichia coli, Shigella flexneri, Salmonella typhi, Pseudomonas aeruginosa, and Klebsiella pneumonia and 2 Gram positive bacteria, Listeria monocytogenes and Bacillus cereus. The methanolic extract exhibited inhibitory effects against most of the tested microorganisms with zone of inhibition ranging from (11-39 mm). The largest inhibition zone were obtained from the methanolic extract of Acacia nilotica (fruits) against the Gram negative Salmonella typhi (39mm) in 100 mg/ml concentration, and Gram positive Bacillus cereus (30mm) in 100 mg/ml concentration comparison with Gentamicin (10μg/disc). These studies conducted for A. nilotica (fruits) was proved to have potent activities against clinical isolated bacteria in vitro and was considered as treatment of several bacterial and viral infections.
How to cite this article:
Sara M Gmaraldeen, Amira A Magzoub, Ali M Badri, Mohamed I Garbi, Mahmmoud S Saleh. Antibacterial activity of Acacia nilotica fruits extract against pathogenic bacteria. Int J Appl Res 2016;2(6):103-106.