International Journal of Applied Research
Vol. 2, Issue 6, Part G (2016)
Candida biofilm: A study on characterisation, speciation and a comparative analysis of the effects of antifungal drugs on biofilm producers and non- biofilm producers
Microbes build bioﬁlms which is the potential cause of persistent infections which acts as the defense against host immune system and finally results in resistance to antimicrobial treatment. Candida
is the most common opportunistic fungal pathogen among immunocompromised individuals.
Aims and objectives: To compare the effect of Antifungal drugs on biofilm producers and non-biofilm producers among Candida isolates.
Materials and Methods: Candida species isolated from the clinical materials received in our laboratory were identified by conventional methods. Biofilm formation was tested by tube method. Antifungal susceptibility was done and results were compared between biofilm producers and non-biofilm producers.
Results: Fifty four Candida species were isolated over a period of 3 months, of which C. albicans were 63% followed by C. tropicalis 24% and C. krusei 13%. Out of which 41% of C. albicans and 16% of C. tropicalis and 9% of C. krusei were biofilm producers.
Conclusion: Biofilm producers of C. albicans and C. tropicalis showed higher resistance to antifungal drugs in this study.
How to cite this article:
Abirami Pragaspathy, Meera Meundi, Shreeshma P. Candida biofilm: A study on characterisation, speciation and a comparative analysis of the effects of antifungal drugs on biofilm producers and non- biofilm producers. Int J Appl Res 2016;2(6):405-407.