Vol. 3, Issue 1, Part L (2017)

Background: The aggregate expenses associated with direct medical treatment and job absenteeism resulting from chronic rhinosinusitis induced by Sinonasal Polyposis are considerable. In the pathophysiology of Chronic Rhinosinusitis, inflammation plays a pivotal role, and a diverse array of pharmaceutical interventions, such as topical corticosteroids, antibiotics, saline irrigations, and systemic steroids, are accessible for its treatment.

Materials and Methods: The present investigation was carried out in the Department of Pediatric, Mayo Institute of Medical Sciences, located in Barabanki, Uttar Pradesh, India, over the period spanning from November 2015 to October 2016. This study examines a cohort of forty individuals diagnosed with chronic rhinosinusitis and sinonasal polyposis. This trial involved the administration of systemic steroids to a cohort of 20 patients, with the remaining 20 patients receiving placebos. Operative and clinical information underwent a rigorous process of critical data analysis.

Results: The present study is a double-blind, placebo-controlled experiment that aims to evaluate the efficacy of pre- and post-operative systemic steroids in enhancing surgical outcomes for patients having endoscopic subcutaneous sleeve surgery (ESS) for the management of chronic renal failure with postoperative pain (CRSwP). Emotional and objective indices of achievement were utilized in our study. The primary objective of the study was to investigate the impact of steroid utilization on subjective and objective indicators of well-being.

Conclusion: Adjuvant steroids, when administered, have the potential to mitigate postoperative complications such as scarring, synechiae development, postoperative crusting, and recurrence.