International Journal of Applied Research
Vol. 3, Issue 10, Part E (2017)
Anti-diabetic activity of isolated fractions of Vigna radiata and Allmania nodiflora in streptozotocin induced diabetic rats
The present study focuses on the determination of the anti-diabetic activity of the extracted fractions of the seeds of Vigna radiata; Fabaceae family and whole plant of Allmania nodiflora; Amaranthaceae family in rats with diabetes induced through STZ. The 20 mg/kg and 40 mg/kg doses of Vigna radiate and Allmania nodiflora were given to the rats for 28 days. The antidiabetic activity was compared to the standard pioglitazone at a dose of 2.7 mg/kg, by measuring blood glucose through accu-chek active test meter. The results revealed that Vigna radiata had significant anti-diabetic activity. Also, the Vigna radiata remained safe till 300 mg/kg in acute toxic and 1000 mg/kg in sub-acute toxic studies and had photochemically. From these findings it can be inferred that Vigna radiata has lowered FBG in experimentally induced diabetic rats.
How to cite this article:
Venkat Rao Ravuri, Dr. AVVS Swamy. Anti-diabetic activity of isolated fractions of Vigna radiata and Allmania nodiflora in streptozotocin induced diabetic rats. Int J Appl Res 2017;3(10):366-371.