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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

IMPACT FACTOR (RJIF): 8.4

International Journal of Applied Research

Vol. 3, Issue 10, Part E (2017)

Anti-diabetic activity of isolated fractions of Vigna radiata and Allmania nodiflora in streptozotocin induced diabetic rats

Author(s)
Venkat Rao Ravuri and Dr. AVVS Swamy
Abstract
The present study focuses on the determination of the anti-diabetic activity of the extracted fractions of the seeds of Vigna radiata; Fabaceae family and whole plant of Allmania nodiflora; Amaranthaceae family in rats with diabetes induced through STZ. The 20 mg/kg and 40 mg/kg doses of Vigna radiate and Allmania nodiflora were given to the rats for 28 days. The antidiabetic activity was compared to the standard pioglitazone at a dose of 2.7 mg/kg, by measuring blood glucose through accu-chek active test meter. The results revealed that Vigna radiata had significant anti-diabetic activity. Also, the Vigna radiata remained safe till 300 mg/kg in acute toxic and 1000 mg/kg in sub-acute toxic studies and had photochemically. From these findings it can be inferred that Vigna radiata has lowered FBG in experimentally induced diabetic rats.
Pages: 366-371  |  180 Views  8 Downloads
How to cite this article:
Venkat Rao Ravuri, Dr. AVVS Swamy. Anti-diabetic activity of isolated fractions of Vigna radiata and Allmania nodiflora in streptozotocin induced diabetic rats. Int J Appl Res 2017;3(10):366-371.
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International Journal of Applied Research