International Journal of Applied Research
Vol. 3, Issue 2, Part B (2017)
Acute phase reactants- Diagnostic VS prognostic significance: An overview
Dr. Rizwan Sanadi, Dr. Laksha Chelani, Dr. Meenu Pillai and Dr. Jyotsna Anjankar
Acute phase reaction is a general term attributed to a group of systemic and metabolic changes that occur within hours of an inflammatory stimulus. The most important component of this response is the acute phase proteins, which are a heterogenous group of plasma proteins. If the inflammatory response is self-limiting or treated, level of these proteins returns to normal within days or weeks. A stronger stimulus for inflammation will result in greater change in the concentration of acute phase proteins. The production of these proteins is regulated to a great extent by cytokines and to a lesser extent by glucocorticoid hormones. They bind to bacteria leading to activation of complement proteins that destroy pathogenic organisms.
This article highlights the features, functions, synthesis and types of acute-phase proteins and their associated relation in periodontal disease.
How to cite this article:
Dr. Rizwan Sanadi, Dr. Laksha Chelani, Dr. Meenu Pillai, Dr. Jyotsna Anjankar. Acute phase reactants- Diagnostic VS prognostic significance: An overview. Int J Appl Res 2017;3(2):94-97.