Vol. 3, Issue 6, Part J (2017)

Methods:The research conducted was both prospective and randomized. Following a comprehensive examination of the methodology, the research was conducted on a sample of 60 eligible participants, with the explicit approval of an ethics committee and the explicit informed consent of the patients. The study was conducted at Department of General Medicine, Maheshwara Medical College & Hospital, Chitkul, Sangareddy, Telangana, Indiabetween January 2016 to December 2016.

Results:The study group saw a reduction in intraocular pressure following the administration of premedication. Following succinylcholine administration and intubation, intraocular pressure (IOP) increased in all three groups. However, in both the study and control groups, IOP did not surpass the levels observed before treatment. Both doses effectively inhibited the sympathetic response to laryngoscopy and intubation, however the highest level of hemodynamic stability was achieved at a dosage of 0.4 g/kg.

Conclusion:Both dosages of dexmedetomidine are equally effective in avoiding a rise in intraocular pressure (IOP) and reducing the sympathetic response. However, it has been observed that administering a dosage of 0.4 g/kg is linked to enhanced hemodynamic stability. Therefore, administering dexmedetomidine at a dosage of 0.4 g/kg may be beneficial in preventing an elevation in intraocular pressure.