Vol. 3, Issue 6, Part Q (2017)

Abstract
Despite increasing application of silver nanoparticles (NPs) in industry and consumer products there is still little known about their potential toxicity, particularly to organism in aquatic environment. To investigate the fate and effect of silver NPs in fish Clarias batrachus. The histological alterations in the kidney of a freshwater catfish Clarias batrachus exposed to sublethal concentration silver nanoparticle. The kidney exhibited shrinkage of glomeruli but the tubular structure was not affected after 10 days of 0.10mg/l silver nanoparticle. The glomeruli were further shurnkened along with the widening of tubular luman after 20 days of exposure. In the fishes exposed to 0.16 mg/l silver nanoparticle (10nm), the kidney showed distorted glomerular organization leaving a mass of cell and swollen tubular after 10 days of exposure. The epithelial cells of the tubules have lost the cell membranes and the area of lumen was now decreased after 20 days of exposure of silver nanoparticle. Therefore it is inferred that the harmful impact of silver nanoparticle on the kidney is dose and time dependent.