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International Journal of Applied Research
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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

IMPACT FACTOR (RJIF): 8.4

Vol. 4, Issue 10, Part B (2018)

Latex Agglutination test for the early diagnosis of Cryptococcal meningitis

Latex Agglutination test for the early diagnosis of Cryptococcal meningitis

Author(s)
Dr. Mathure TV, Dr. Vaidya SP, Dr. Deshpande SD, Dr. Mehta P and Dr. Koppikar GV
Abstract
Cryptococcal infection which may cause meningitis is the most prevalent and common invasive fungal infection. Serodiagnosis is an important adjunct for rapid diagnosis of Cryptococcosis. In the present study, antigen detection using CALAS meridian diagnostic kit was evaluated along with other traditional methods in Nair Hospital, Mumbai.Out of 100 CSF samples, 20% positivity was observed by only culture method, 21% positivity by microscopy and culture method together, while 22% positivity was observed when all the three methods namely culture, microscopy & LAT were used for the testing of CSF. Microscopy, culture and antigen detection tests were well correlated in the study. Cryptococcal antigen detection from CSF was a useful method for an early diagnosis. The immunological diagnosis of Cryptococcal meningitis by CALAS meridian diagnostic kit was rapid and had 92%-95. 5% sensitivity and specificity.
Pages: 110-113  |  753 Views  61 Downloads
How to cite this article:
Dr. Mathure TV, Dr. Vaidya SP, Dr. Deshpande SD, Dr. Mehta P, Dr. Koppikar GV. Latex Agglutination test for the early diagnosis of Cryptococcal meningitis. Int J Appl Res 2018;4(10):110-113.
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