AbstractBackground: CNS tumors, though not the leading cause of cancer cases, causes significant number of cancer deaths. Five years survival in most of patients with CNS tumors is less than 20%. With the advent of newer diagnostic modalities even in developing countries like India many new cases were diagnosed every year. Due to incomplete registration of cases in India exact frequency is difficult to estimate. Hospital based study can be a good resource to estimate the disease burden.
Objectives: To study the frequency with age and sex distribution of various CNS tumors.
Materials and Methods: It was a ten year retrospective study conducted in the Department of Pathology, Gajra Raja Medical College, Gwalior (M.P.) from January 2007 to December 2016. 1620 cases of CNS neoplasms were collected. Diagnosis were done on the basis of histopathology. Categorisation according to various types with their age and sex distribution was done from these datas.
Result: In adults most common tumors were Astrocytomas (39.27%) followed by Meningiomas (22.72%), Schwannomas, Neurofibromas. In Children most common tumors are Astrocytomas (24.74%) followed by Medulloblastomas (20.10%), Neurofibromas. Except for Meningiomas which showed female preponderance all other tumors are more common in males.
Conclusion: Present study shows similarities with some variations from other studies. Registration of all the cases and molecular profiling will provide better assessment of CNS tumors spectrum and tailoring treatment modalities.