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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF
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Vol. 5, Issue 1, Part D (2019)
Hormone receptor (ER, PR) status in breast carcinoma – correlation with clinicopathological prognostic parameters
Hormone receptor (ER, PR) status in breast carcinoma – correlation with clinicopathological prognostic parameters
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Abstract
Background: Breast is one of the most common cause of death in women. Earlier diagnosis and treatment with appropriate therapy based on hormonal status leads to a reduction in mortality rate. Aim of this study is to assess the hormone receptor status in breast carcinomas and to compare them with other clinical and pathological parameters.
Background: Breast is one of the most common cause of death in women. Earlier diagnosis and treatment with appropriate therapy based on hormonal status leads to a reduction in mortality rate. Aim of this study is to assess the hormone receptor status in breast carcinomas and to compare them with other clinical and pathological parameters.
Materials and methods: This retrospective study was conducted in Department of Pathology, Vishwabharti Medical College, Kurnool, A.P. for a period of 2 years. A total of 52 cases were studied and IHC were done. ER, PR status of patients were studied and compared with other parameters.
Results: Majority of cases were in postmenopausal women. Clinical stage 2 and histological grade 2 cases were more in number. There was significant correlation between clinical staging and NPI sore and between tumor grade and ER, PR status.
Conclusion: ER, PR status has significant correlation with histological grading but does not have significant correlation with clinical staging. So, irrespective staging and other clinical parameters hormonal studies should be conducted in all cases to reduce mortality and recurrences.
Pages: 249-252 | 938 Views 110 Downloads
How to cite this article:
Dr. Mahesh C Patil, Dr. Saurabh Shrivastava. Hormone receptor (ER, PR) status in breast carcinoma – correlation with clinicopathological prognostic parameters. Int J Appl Res 2019;5(1):249-252.
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Research Journals